‘We see increased transmissions, but don’t see a change in severity’: What WHO epidemiologist’s latest Covid update means

Maria Van Kerkhove, an infectious disease epidemiologist at the World Health Organization (WHO), recently emphasized the need for continuous monitoring of the Covid virus, particularly in light of the dominance of the Omicron Variants of Concern worldwide. In a video update shared on the WHO’s Twitter page, Kerkhove explained that approximately 80% of reported sequences globally belong to the BA.5, including its sub-lineages, with XBB identified as a recombinant of two BA.2 sublineages, specifically BA.2.10.1 and B.2.75. She highlighted that this recombinant is one of over 300 sub-lineages of Omicron being tracked globally by the WHO and its partners.

The accompanying message in the video stressed the importance of sustained surveillance of the virus through well-planned and organized testing and sequencing across the globe to assess and formulate appropriate policies.

Kerkhove acknowledged the increasing attention given to rising sublineages, particularly XBB, due to its growth advantage. While there is no signal indicating a change in the severity of the XBB recombinant, she emphasized the need to monitor it closely due to its Omicron classification, numerous mutations, and fitness advantage.

Regarding the ‘BQ.1’ sub-variant of BA.5, Kerkhove mentioned its increased transmissibility but clarified that hospitalization data worldwide does not suggest a change in severity. She reassured that diagnostics and vaccines continue to be effective.

The WHO, on its website, had previously introduced a new category in its variant tracking system for Omicron subvariants under monitoring, signaling to global public health authorities which VOC lineages may require prioritized attention.

Despite the mild nature of the Omicron strain, believed to be responsible for the third wave of infections in India, healthcare professionals emphasized the importance of continued vigilance. Dr. Ravi Shekhar Jha from Fortis Hospitals, Faridabad, emphasized the need for full Covid vaccination and adherence to appropriate behavior. Dr. Monalisa Sahu from Yashoda Hospitals, Hyderabad, echoed this sentiment, especially for vulnerable populations. They emphasized the potential for the mutated virus to evolve into a more dangerous variant, underscoring the importance of precautions.

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